Pterostilbene inhibits non-small cell lung cancer progression by activating the STING pathway and enhancing antitumor immune response

IntroductionNon-small cell lung cancer (NSCLC) is a leading cause of cancer-related mortality, and current therapies often yield limited efficacy. This study investigated the antitumor potential and mechanisms of Pterostilbene (PTE), a natural stilbenoid with superior bioavailability.MethodsThe anti...

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Principais autores:	Li-Ping Kang, Han Xie, Hua-Jing Huang, Pan Xu, Cong Xu, Dong-Hui Huang, Ze-Bo Jiang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-10-01
coleção:	Frontiers in Immunology
Assuntos:	pterostilbene non-small cell lung cancer STING pathway reactive oxygen species CD8+ T tumor microenvironment
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1622284/full
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