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Modulation of the immunological and neuroinflammatory microenvironment in older people with multiple sclerosis

Life expectancy and the age at onset of multiple sclerosis (MS) are increasing, and a growing proportion of people with MS (pwMS) are now older than 55–60 years. Aging modifies MS pathobiology, with the dominant disease mechanisms moving from focal, relapse-driven inflammation to chronic, compartmen...

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Principais autores: Celia Oreja-Guevara, Sven G. Meuth, Nikos Grigoriadis, Patrick Vermersch, Hans Peter Hartung, Per Soelberg Sörensen, Letizia Leocani, Klaus Schmierer, Ralf Gold, Óscar Fernández
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-06-01
coleção:Frontiers in Immunology
Assuntos:
aging
immunosenescence
inflammaging
multiple sclerosis
neuroinflammation
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1832582/full
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