A secreted schistosome cathepsin B1 cysteine protease and acute schistosome infection induce a transient T helper 17 response.
The natural history of schistosome infection in the mammalian host is determined by CD4+ T helper responses mounted against different parasite life cycle stages. A T helper 2 (TH2) response to schistosome eggs is required for host survival and establishment of chronic infection. However, a TH2 cell-...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science (PLoS)
2019-01-01
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| Collection: | PLoS Neglected Tropical Diseases |
| Accès en ligne: | https://doi.org/10.1371/journal.pntd.0007070 |
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