Conformational spread drives the evolution of the calcium–calmodulin protein kinase II
Abstract The calcium calmodulin (Ca2+/CaM) dependent protein kinase II (CaMKII) decodes Ca2+ frequency oscillations. The CaMKIIα isoform is predominantly expressed in the brain and has a central role in learning. I matched residue and organismal evolution with collective motions deduced from the ato...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Portfolio
2022-05-01
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| Collection: | Scientific Reports |
| Accès en ligne: | https://doi.org/10.1038/s41598-022-12090-y |
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