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Unravelling the γ-butyrolactone network in Streptomyces coelicolor by computational ensemble modelling.

Antibiotic production is coordinated in the Streptomyces coelicolor population through the use of diffusible signaling molecules of the γ-butyrolactone (GBL) family. The GBL regulatory system involves a small, and not completely defined two-gene network which governs a potentially bi-stable switch b...

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Bibliografische gegevens
Hoofdauteurs: Areti Tsigkinopoulou, Eriko Takano, Rainer Breitling
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2020-07-01
Reeks:PLoS Computational Biology
Online toegang:https://doi.org/10.1371/journal.pcbi.1008039
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