Time-series transcriptomic analysis of cigarette smoke–associated lung responses reveals COPD-related inflammatory and epithelial remodeling modules in murine models

BackgroundCigarette smoke is the major environmental risk factor for chronic obstructive pulmonary disease (COPD), driving progressive lung inflammation and tissue injury. However, distinguishing general smoke-responsive transcriptional changes from COPD-related molecular signatures remains challeng...

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Автори:	Meng Long, Anhuizi Qiu, Wangyu Jiang, Fangya Guo, Siyi Tu, Fang Chen
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Frontiers Media S.A. 2026-06-01
Серія:	Frontiers in Medicine
Предмети:	bioinformatics candidate genes chronic obstructive pulmonary disease cigarette smoke time-series transcriptomics
Онлайн доступ:	https://www.frontiersin.org/articles/10.3389/fmed.2026.1785075/full
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