CIITA and its dual roles in MHC gene transcription
CIITA is a transcriptional co-activator that regulates γ-interferon-activated transcription of Major Histocompatibility Complex (MHC) class I and class II genes. As such, it plays a critical role in immune responses: CIITA deficiency results in aberrant MHC gene expression and consequently in autoim...
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| Principais autores: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2013-12-01
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| Serier: | Frontiers in Immunology |
| Fag: | |
| Online adgang: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00476/full |
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