Genomic and microenvironmental heterogeneity shaping epithelial-to-mesenchymal trajectories in cancer

The intermediate states of the epithelial-to-mesenchymal transition (EMT) in cancer require further molecular characterisation. Here, the authors develop a method to evaluate EMT transformation and trajectories in cancer transcriptomics data, characterising EMT macro-states, including a hybrid state...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Guidantonio Malagoli Tagliazucchi, Anna J. Wiecek, Eloise Withnell, Maria Secrier
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2023-02-01
Schriftenreihe:	Nature Communications
Online-Zugang:	https://doi.org/10.1038/s41467-023-36439-7
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