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Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA

Background: Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation and imbalances in lipid metabolism in the liver. Although nuclear receptors (NRs) play a crucial role in hepatic lipid metabolism, the underlying mechanisms of NR regulation in NAFLD remain largely...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Yo Han Lee, Hyun-Jun Jang, Sounkou Kim, Sun Sil Choi, Keon Woo Khim, Hye-jin Eom, Jimin Hyun, Kyeong Jin Shin, Young Chan Chae, Hongtae Kim, Jiyoung Park, Neung Hwa Park, Chang-Yun Woo, Chung Hwan Hong, Eun Hee Koh, Dougu Nam, Jang Hyun Choi
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2021-12-01
Schriftenreihe:eLife
Schlagworte:
miR-20b
NAFLD
PPARα
combination therapy
Online-Zugang:https://elifesciences.org/articles/70472
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