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A prospective observational cohort study: neurotoxic processes associated with psychiatric symptoms in heroin use disorder: the kynurenine pathway and neopterin levels

AimThis study investigated the effects of tryptophan (TRP) metabolism, kynurenine pathway (KP) and neopterin levels in heroin use disorder (HUD) in relation to neurotoxicity, treatment processes and psychiatric recovery.MethodThe study groups consisted of patients with HUD who sought treatment at th...

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Principais autores: Güleser Akpınar, Mehtap Sarıoğlu, Gözde Girgin, Terken Baydar, Hande Sipahi
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2026-04-01
Series:Frontiers in Psychiatry
Assuntos:
heroin use disorder
kynurenine pathway
neopterin
neuroinflammation
psychiatric symptoms
tryptophan metabolism
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fpsyt.2026.1785477/full
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