BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Bone morphogenetic protein (BMP) antagonists have been increasingly linked to the development of colorectal cancer (CRC). BMP signalling operates in opposition to the WNT signalling pathway, which sustains stem‐cell maintenance and self‐renewal of the normal intestinal epithelium. Reduced BMP and el...

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Bibliographic Details

Main Authors:	Eloise Clarkson, Annabelle Lewis
Format:	Artigo
Language:	Inglês
Published:	Wiley 2025-11-01
Series:	Molecular Oncology
Subjects:	bone‐morphogenic protein cancer stem cell chordin‐like 2 colorectal cancer WNT signalling pathway
Online Access:	https://doi.org/10.1002/1878-0261.70064
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