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Identification of an evolutionarily conserved cis-regulatory element controlling the Peg3 imprinted domain.

The mammalian Peg3 domain harbors more than 20 evolutionarily conserved regions (ECRs) that are spread over the 250-kb genomic interval. The majority of these ECRs are marked with two histone modifications, H3K4me1 and H3K27ac, suggesting potential roles as distant regulatory elements for the transc...

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書誌詳細
主要な著者: Michelle M Thiaville, Hana Kim, Wesley D Frey, Joomyeong Kim
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2013-01-01
シリーズ:PLoS ONE
オンライン・アクセス:http://europepmc.org/articles/PMC3769284?pdf=render
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