Adamantane-thiazole hybrids and related derivatives: synthesis, crystal structures, in vitro antibacterial, antifungal, and anti-proliferative activities

Abstract Series of 2-(adamantan-2-ylidene)-N-substituted hydrazine-1-carbothioamide derivatives 5a-d and (E)-2-[(adamantan-2-ylidene)hydrazono]-3,4-diaryl-2,3-dihydrothiazole derivatives 7a-l were prepared and their structures were confirmed. In vitro antimicrobial evaluation of compounds 5a-d and 7...

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Principais autores:	Heidi S. Abd El-Monaem, Mahmoud B. El-Ashmawy, Naglaa I. Abdel-Aziz, Olivier Blacque, E. Habib, Subbiah Thamotharan, Ali A. El-Emam
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2026-01-01
Series:	BMC Chemistry
Assuntos:	Adamantane Thiazole Antimicrobial activity Anti-proliferative activity Single crystal XRD Molecular docking
Acceso en liña:	https://doi.org/10.1186/s13065-025-01706-9
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