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Asialoglycoprotein receptor 1 promotes SARS-CoV-2 infection of human normal hepatocytes

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes multi-organ damage, which includes hepatic dysfunction, as observed in over 50% of COVID-19 patients. Angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2) is the primary receptor for SARS-CoV-2 entry into host...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Xinyi Yang, Xu Zheng, Yuqi Zhu, Xiaying Zhao, Jun Liu, Jiangna Xun, Songhua Yuan, Jun Chen, Hanyu Pan, Jinlong Yang, Jing Wang, Zhimin Liang, Xiaoting Shen, Yue Liang, Qinru Lin, Huitong Liang, Min Li, Fei Peng, Daru Lu, Jianqing Xu, Hongzhou Lu, Shibo Jiang, Ping Zhao, Huanzhang Zhu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2024-02-01
Schriftenreihe:Signal Transduction and Targeted Therapy
Online-Zugang:https://doi.org/10.1038/s41392-024-01754-y
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