New Anti‐Angiogenic Therapy for Glioblastoma With the Anti‐Depressant Sertraline

ABSTRACT Background and Aims Anti‐angiogenic therapies prolong patient survival in some malignancies but not glioblastoma. We focused on the relationship between the differentiation of glioma stem like cells (GSCs) into tumor derived endothelial cells (TDECs) and, anti‐angiogenic therapy resistance....

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Nobushige Tsuboi, Yoshihiro Otani, Atsuhito Uneda, Joji Ishida, Yasuki Suruga, Yuji Matsumoto, Atsushi Fujimura, Kentaro Fujii, Hideki Matsui, Kazuhiko Kurozumi, Isao Date, Hiroyuki Michiue
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2024-10-01
Schriftenreihe:	Cancer Medicine
Schlagworte:	anti‐angiogenic therapy antidepressant sertraline drug repositioning glioblastoma tumor derived endothelial cells
Online-Zugang:	https://doi.org/10.1002/cam4.70288
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