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Calcium supplementation for prevention of pre-eclampsia in high-risk women: study protocol for a randomised triple-blind placebo-controlled trial (CaPE)

Abstract Background Pre-eclampsia is a multisystem disorder affecting 2.8% of pregnancies in the UK. It usually presents after 20-week gestation with new-onset high blood pressure and proteinuria. Complications include eclampsia, stroke, and HELLP syndrome for the mother and preterm birth, fetal gro...

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Principais autores: Shireen Meher, Alisha Maher, Peter Brocklehurst, Lucy Chappell, Andrew Ewer, Marcus Green, Fadil M. Hannan, Kim Hinshaw, Max Hughes, Louise Jackson, Patrick Moore, Katie Morris, Rachel Plachcinski, Julia Sanders, Lee Middleton
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-03-01
Serier:Trials
Fag:
Pre-eclampsia
Hypertension
Calcium
Pregnancy
High risk
Randomised controlled trial
Online adgang:https://doi.org/10.1186/s13063-026-09513-w
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