Unprecedented Epimerization of an Azithromycin Analogue: Synthesis, Structure and Biological Activity of 2′-Dehydroxy-5″-Epi-Azithromycin

Certain macrolide antibiotics, azithromycin included, possess anti-inflammatory properties that are considered fundamental for their efficacy in the treatment of chronic inflammatory diseases, such as diffuse pan-bronchiolitis and cystic fibrosis. In this study, we disclose a novel azithromycin anal...

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Principais autores:	Goran Kragol, Victoria A. Steadman, Zorica Marušić Ištuk, Ana Čikoš, Martina Bosnar, Dubravko Jelić, Gabrijela Ergović, Marija Trzun, Berislav Bošnjak, Ana Bokulić, Jasna Padovan, Ines Glojnarić, Vesna Eraković Haber
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2022-02-01
Serija:	Molecules
Teme:	macrolides Barton–McCombie oxidation azithromycin anti-inflammatory activity
Online dostop:	https://www.mdpi.com/1420-3049/27/3/1034
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