Postoperative loss of perineuronal nets in the hippocampal CA1 region results in memory consolidation deficits

Postoperative cognitive dysfunction (POCD) is a common postoperative neurological complication, with memory consolidation deficits being one of its prominent features. However, the mechanisms underlying postoperative memory consolidation deficits are still unclear. The perineuronal net (PNN) is a sp...

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Autors principals:	Zun-sai Feng, Jiang-nan Wu, Gui-cheng Wang, Zi-qing Xu, Yan-jing Guo, Shi-yu Hao, Gong-ming Wang, Meng-yuan Zhang
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2025-09-01
Col·lecció:	Brain Research Bulletin
Matèries:	Postoperative cognitive dysfunction Memory consolidation Perineuronal net Parvalbumin interneurons Microglia
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S036192302500245X
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