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Backbone assignment and inhibitor binding studies of IL-33 mutants by NMR spectroscopy

Abstract Interleukin-33 (IL-33) is an IL-1 family protein that induces a type-2 immune response. IL-33 is constitutively expressed in epithelial cells and released in response to the cell damage or stimulation by an allergen. The secreted protein is activated when the N-terminal domain is cleaved by...

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Autores principales: Minhee Kang, Soyun Kim, Chan Haeng Heo, Sang-Hyun Son, Youngjoo Byun, Young Ho Jeon
Formato: Artigo
Lenguaje:Inglês
Publicado: SpringerOpen 2023-07-01
Colección:Journal of Analytical Science and Technology
Acceso en línea:https://doi.org/10.1186/s40543-023-00392-3
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