Letrozole effectively treats peripheral precocious puberty in a girl with McCune-Albright syndrome: a case report and review of the literature

Abstract McCune-Albright syndrome (MAS) is a rare disorder caused by somatic GNAS gene mutations, characterized by peripheral precocious puberty (PPP), café-au-lait spots, and fibrous dysplasia of bone (FD). This case report details a 3-year-and-10-month-old girl presenting with vaginal bleeding, sc...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Yutao Xie, Jinhua Huang, Zhixiang Zheng, Yanning Yang, Xiaoling Liang, Jieting Chen, Yina She, Yiwen Guo, Danling Guo, Meiqing Xie
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-04-01
coleção:	BMC Pediatrics
Assuntos:	McCune-Albright syndrome Letrozole Peripheral precocious puberty Aromatase inhibitors Gonadotropin-independent precocious puberty
Acesso em linha:	https://doi.org/10.1186/s12887-026-06800-y
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!