Microbial spectrum, co-detection patterns, and clinical correlations in 10,153 hospitalized children with acute respiratory infections: a large-scale tNGS analysis

Abstract Objective This study characterized the microbial spectrum and clinical manifestations in hospitalized children with acute respiratory infections (ARI) using targeted next-generation sequencing (tNGS) and identified predictors for severe disease requiring ICU admission. Methods 10,153 hospit...

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Hoofdauteurs:	Chunyun Fu, Junming Lu, Xuehua Hu, Ya Huang, Jiangyang Zhao, Guangbing Liu, Lishai Mo, Jielin Chen, Wenting Tang, Yili Zhang, Qiang Huang, Yanhua Feng, Yanqing Tang, Jiaqi Wen, Ruting Chen, Cuihong Lu, Renye Yao, Shangjuan zeng, Xiangjun Lu, She Liang, Yan Chen, Jialing Ruan, Ning Zhu, Ziyin Huang, Shang Yi, Hao Wei, Huiping Huang, Xiaoying Chen, Qifei Li, Jie Tan
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2026-04-01
Reeks:	Journal of Translational Medicine
Onderwerpen:	Respiratory infections Microbial spectrum Co-detection Pediatric patients tNGS
Online toegang:	https://doi.org/10.1186/s12967-026-08164-4
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