Association of loss of heterozygosity with cytogenetic abnormalities in acute myeloid leukemia and myelodysplastic syndrome

Deletions on chromosomes 5 and 7 are frequently seen in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). It is assumed that these deletions indicate loss of tumor suppressor genes on these chromosomes and until these tumor suppressor genes are identified, the functional consequences...

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Autores principales:	R.F. Pinheiro, F.M. Serio, M.R.R. Silva, M.R.S. Briones, M.L.L.F. Chauffaille
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Associação Brasileira de Divulgação Científica 2008-07-01
Colección:	Brazilian Journal of Medical and Biological Research
Materias:	Myelodysplastic syndrome Acute myeloid leukemia Cytogenetic abnormalities Loss of heterozygosity
Acceso en línea:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000700010
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