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Host genetics and tumor environment determine the functional impact of neutrophils in mouse tumor models

Background Neutrophils have been reported to have protumor, antitumor or neutral effects in cancer progression. The underlying causes for this functional variability are not clear.Methods We studied the role of neutrophils in six different mouse tumor models by intratumoral injection of antimicrobia...

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Bibliographic Details
Main Authors: Hailiang Mei, Sjoerd H van der Burg, Ramon Arens, Thorbald van Hall, Guillaume Beyrend, Jan Willem Kleinovink, Marit van Elsas, Matthijs Moerland, Gary Feiss, Peter H Nibbering, Silvana M Jirka
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2020-10-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e000877.full
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