Prohibitin 1 interacts with p53 in the regulation of mitochondrial dynamics and chemoresistance in gynecologic cancers

Abstract Background Mitochondrial dynamics (e.g. fission/fusion) play an important role in controlling chemoresistance in representative gynecologic malignancies, ovarian and cervical cancer. Processing the long form of Optic atrophy (L-Opa)1 is a distinctive character of mitochondrial fragmentation...

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Autori principali:	Bao Kong, Chae Young Han, Se Ik Kim, David A. Patten, Youngjin Han, Euridice Carmona, Dar-Bin Shieh, Annie C. Cheung, Anne-Marie Mes-Masson, Mary-Ellen Harper, Yong Sang Song, Benjamin K. Tsang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2022-06-01
Serie:	Journal of Ovarian Research
Soggetti:	Phb1 p53 Bak CDDP Mitochondrial fragmentation Chemoresistance
Accesso online:	https://doi.org/10.1186/s13048-022-00999-x
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