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The effect of the first-generation HCV-protease inhibitors boceprevir and telaprevir and the relation to baseline NS3 resistance mutations in genotype 1: experience from a small Swedish cohort

Background: The clinical experience with protease-inhibitor (PI) triple regimen appears disappointing regarding effect, side effects, high work load, and costs. This real-world study evaluates baseline and emerging resistance-associated substitutions (RASs) and their significance for treatment outco...

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Библиографические подробности
Главные авторы: Midori Kjellin, Terése Wesslén, Erik Löfblad, Johan Lennerstrand, Anders Lannergård
Формат: Artigo
Язык:Inglês
Опубликовано: Upsala Medical Society 2018-01-01
Серии:Upsala Journal of Medical Sciences
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Online-ссылка:http://dx.doi.org/10.1080/03009734.2018.1441928
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