Thiamine and benfotiamine protect neuroblastoma cells against paraquat and β-amyloid toxicity by a coenzyme-independent mechanism

Background: Benfotiamine (BFT) is a synthetic thiamine precursor with high bioavailability. It is efficient in treating complications of type 2 diabetes and has beneficial effects in mouse models of neurodegenerative diseases. The mechanism of action of BFT remains unknown, though it is sometimes su...

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Detalhes bibliográficos

Principais autores:	Margaux Sambon, Aurore Napp, Alice Demelenne, Julie Vignisse, Pierre Wins, Marianne Fillet, Lucien Bettendorff
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2019-05-01
coleção:	Heliyon
Assuntos:	Cell biology Neuroscience
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2405844018358870
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