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Effect of Caffeine and Other Methylxanthines on Aβ-Homeostasis in SH-SY5Y Cells

Methylxanthines (MTX) are alkaloids derived from the purine-base xanthine. Whereas especially caffeine, the most prominent known MTX, has been formerly assessed to be detrimental, this point of view has changed substantially. MTXs are discussed to have beneficial properties in neurodegenerative dise...

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Principais autores: Daniel Janitschke, Christopher Nelke, Anna Andrea Lauer, Liesa Regner, Jakob Winkler, Andrea Thiel, Heike Sabine Grimm, Tobias Hartmann, Marcus Otto Walter Grimm
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-11-01
coleção:Biomolecules
Assuntos:
caffeine
theophylline
theobromine
propentofylline
pentoxifylline
methylxanthin
amyloid-β
amyloid precursor protein
alzheimer’s disease
oxidative stress
Acesso em linha:https://www.mdpi.com/2218-273X/9/11/689
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