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FRET-Based Sorting of Live Cells Reveals Shifted Balance between PLK1 and CDK1 Activities During Checkpoint Recovery

Cells recovering from the G2/M DNA damage checkpoint rely more on Aurora A-PLK1 signaling than cells progressing through an unperturbed G2 phase, but the reason for this discrepancy is not known. Here, we devised a method based on a FRET reporter for PLK1 activity to sort cells in distinct populatio...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Lorenzo Lafranchi, Erik Müllers, Dorothea Rutishauser, Arne Lindqvist
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2020-09-01
Rangatū:Cells
Ngā marau:
Urunga tuihono:https://www.mdpi.com/2073-4409/9/9/2126
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