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Induction of Apoptosis in MCF-7 Cells via Oxidative Stress Generation, Mitochondria-Dependent and Caspase-Independent Pathway by Ethyl Acetate Extract of Dillenia suffruticosa and Its Chemical Profile.

Dillenia suffruticosa, which is locally known as Simpoh air, has been traditionally used to treat cancerous growth. The ethyl acetate extract of D. suffruticosa (EADs) has been shown to induce apoptosis in MCF-7 breast cancer cells in our previous study. The present study aimed to elucidate the mole...

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Detalhes bibliográficos
Principais autores: Yin Sim Tor, Latifah Saiful Yazan, Jhi Biau Foo, Agustono Wibowo, Norsharina Ismail, Yoke Kqueen Cheah, Rasedee Abdullah, Maznah Ismail, Intan Safinar Ismail, Swee Keong Yeap
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4457850?pdf=render
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