Evaluation of MLPA as a comprehensive molecular cytogenetic tool to detect cytogenetic markers of chronic lymphocytic leukemia in Egyptian patients

Abstract Background Chronic lymphocytic leukemia (CLL) is the most common form of adult leukemia. This disease is genetically heterogeneous, and approximately 85% of patients with CLL harbor chromosomal aberrations that are considered effective prognostic biomarkers. The most frequent aberrations in...

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Bibliografiske detaljer

Principais autores:	Ola M. Eid, Rania M. A. Abdel Kader, Lamiaa A. Fathalla, Amany H. Abdelrahman, Ahmed Rabea, Rana Mahrous, Maha M. Eid
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2021-06-01
Serier:	Journal of Genetic Engineering and Biotechnology
Fag:	Chronic lymphocytic leukemia (CLL) Chromosomal aberrations Multiplex ligation-dependent probe amplification (MLPA) Fluorescence in situ hybridization (FISH)
Online adgang:	https://doi.org/10.1186/s43141-021-00198-z
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