Loss of Jag1 cooperates with oncogenic Kras to induce pancreatic cystic neoplasms
Jag1 functions as a tumor suppressor in delaying pancreatic cancer precursor, while at the same time, promotes a phenotypic switch from benign cystic lesions to invasive carcinoma of the pancreas. Notch signaling exerts both oncogenic and tumor-suppressive functions in the pancreas. In this study, d...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Life Science Alliance LLC
2021-02-01
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| coleção: | Life Science Alliance |
| Acesso em linha: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.201900503 |
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