Structural Changes, Biological Consequences, and Repurposing of Colchicine Site Ligands
Microtubule-targeting agents (MTAs) bind to one of several distinct sites in the tubulin dimer, the subunit of microtubules. The binding affinities of MTAs may vary by several orders of magnitude, even for MTAs that specifically bind to a particular site. The first drug binding site discovered in tu...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI AG
2023-05-01
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| Collection: | Biomolecules |
| Sujets: | |
| Accès en ligne: | https://www.mdpi.com/2218-273X/13/5/834 |
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