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Tumor subtypes and signature model construction based on chromatin regulators for better prediction of prognosis in uveal melanoma

Background: Uveal Melanoma (UM) is the most prevalent primary intraocular malignancy in adults. This study assessed the importance of chromatin regulators (CRs) in UM and developed a model to predict UM prognosis.Methods: Gene expression data and clinical information for UM were obtained from public...

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Main Authors: Yue Li, Chao Xiong, Li Li Wu, Bo Yuan Zhang, Sha Wu, Yu Fen Chen, Qi Hua Xu, Hong Fei Liao
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2023-06-01
Series:Pathology and Oncology Research
Subjects:
prognosis
uveal melanoma
TCGA
chromatin regulators
tumor subtypes
Online Access:https://www.por-journal.com/articles/10.3389/pore.2023.1610980/full
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