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Age and frailty in anticancer drug regulatory assessment: a comprehensive cohort study of European marketing authorisations 2012-2023

Background: Prevalence of cancer increases with age, but older adults remain underrepresented in pivotal clinical trials. We analysed the representation of older adults and poor performance score patients in initial marketing authorisation (MA) of new anticancer medicines in the European Union (EU)....

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Váldodahkkit: O. Tenhunen, K. Penttinen, C. Voltz, H. Kuitunen, M. Turpeinen
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Elsevier 2026-03-01
Ráidu:ESMO Real World Data and Digital Oncology
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Liŋkkat:http://www.sciencedirect.com/science/article/pii/S2949820125005521
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