PRMT5 Associates With the FOXP3 Homomer and When Disabled Enhances Targeted p185erbB2/neu Tumor Immunotherapy

Regulatory T cells (Tregs) are a subpopulation of T cells that are specialized in suppressing immune responses. Here we show that the arginine methyl transferase protein PRMT5 can complex with FOXP3 transcription factors in Tregs. Mice with conditional knock out (cKO) of PRMT5 expression in Tregs de...

Volledige beschrijving

Bibliografische gegevens

Hoofdauteurs:	Yasuhiro Nagai, Mei Q. Ji, Fuxiang Zhu, Yan Xiao, Yukinori Tanaka, Taku Kambayashi, Shigeyoshi Fujimoto, Michael M. Goldberg, Hongtao Zhang, Bin Li, Takuya Ohtani, Mark I. Greene
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Frontiers Media S.A. 2019-02-01
Reeks:	Frontiers in Immunology
Onderwerpen:	PRMT5 FOXP3 regulatory T cells autoimmunity scurfy tumor immunity breast cancer
Online toegang:	https://www.frontiersin.org/article/10.3389/fimmu.2019.00174/full
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!