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Role of IL-28B polymorphisms in virologic response to combined pegylated interferon and ribavirin therapy in genotype 4 chronic HCV infected patients with and without cirrhosis

Background: Chronic hepatitis C virus (HCV) represents one of the common causes of chronic liver disease worldwide with Egypt having the highest prevalence, namely genotype 4. The rs12979860 CC genotype of the interleukin 28B (IL28B) polymorphisms is associated with high rates of sustained virologic...

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Hlavní autoři: Amira Youssef Shaala, Mona Gamal Morsi, Reem Abdel Hameed Harfoush, Ehab Hassan ElKhouly, Mohamed Abdel Rahman Ahmed, Mohamed Nabil Roshdy
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer Medknow Publications 2015-09-01
Edice:Alexandria Journal of Medicine
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S2090506814000918
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