The Role of Mitochondrial Dysfunction and Dynamics in Hypertensive Heart Disease: Mechanisms and Recent Advances

Hypertensive heart disease (HHD) is characterized by pressure overload-induced cardiac remodeling, in which mitochondrial dysfunction has emerged as a central contributor to pathophysiology. Mitochondria occupy roughly one-third of the volume of a cardiomyocyte and serve as the primary source of ATP...

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Autors principals:	Bislom C. Mweene, Hanzooma Hatwiko, Joreen P. Povia, Sepiso K. Masenga
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2025-09-01
Col·lecció:	Biology
Matèries:	left ventricular hypertrophy mitochondrial dysfunction aging oxidative stress mitophagy metabolic reprogramming
Accés en línia:	https://www.mdpi.com/2079-7737/14/9/1212
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