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Modulation of the Apoptosis Gene Bcl-x Function Through Alternative Splicing

Apoptosis plays a vital role in cell homeostasis during development and disease. Bcl-x, a member of the Bcl-2 family of proteins, is a mitochondrial transmembrane protein that functions to regulate the intrinsic apoptosis pathway. An alternative splicing (AS) event in exon 2 of Bcl-x results in two...

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Bibliografske podrobnosti
Principais autores: Megan Stevens, Sebastian Oltean
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019-09-01
Serija:Frontiers in Genetics
Teme:
Online dostop:https://www.frontiersin.org/article/10.3389/fgene.2019.00804/full
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