Multidrug Resistance in Cancer Circumvented Using a Cytosolic Drug Reservoir

Abstract It is discovered that sustained cytosolic drug release at a sufficient concentration is an effective mechanism to circumvent multidrug resistance and consequently enhance antitumor drug efficacy. It is showed that a simple way to enable this mechanism is to reach an intracellular kinetic ba...

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Autors principals:	Li Fan, Silu Zhang, Chunyuan Zhang, Chun Yin, Zhiqin Chu, Chaojun Song, Ge Lin, Quan Li
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2018-02-01
Col·lecció:	Advanced Science
Matèries:	circumventing multidrug resistance cytosolic drug concentration cytosolic drug release optical switches self‐decomposable nanoparticles
Accés en línia:	https://doi.org/10.1002/advs.201700289
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