USP4-mediated CENPF deubiquitylation regulated tumor metastasis in colorectal cancer

Abstract Metastasis is a major challenge for colorectal cancer (CRC) treatment. In this study, we identified autophagy activation as a prognostic indicator in CRC and observed that the expression of key autophagy proteins is elevated in metastatic and recurrent cases. Our subsequent goal was to iden...

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書誌詳細

主要な著者:	Zhongdong Xie, Hanbin Lin, Yuecheng Wu, Yanan Yu, Xintong Liu, Yating Zheng, Xiaojie Wang, Jiashu Wu, Meifang Xu, Yuting Han, Qiongying Zhang, Yu Deng, Lin Lin, Yan Linzhu, Li Qingyun, Xinjian Lin, Ying Huang, Pan Chi
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Publishing Group 2025-02-01
シリーズ:	Cell Death and Disease
オンライン･アクセス:	https://doi.org/10.1038/s41419-025-07424-3
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