Dual-functional pH-sensitive nanoliposomes modified with CD47 mimicry peptide enhance icariin delivery to attenuate neuroinflammation and oxidative stress in epilepsy

Around 30 % of patients fail to achieve seizure-free with existing anti-seizure medications (ASMs), and developing drugs that target neuroinflammatory and oxidative stress may benefit patients with refractory epilepsy. The bioactive compound icariin (ICA) isolated from the traditional Chinese medici...

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Detalhes bibliográficos

Principais autores:	Jing Wang, Yangsa Du, Guoting Su, Weiting Tang, Xiaoyan Long, Yongju He, Li Feng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-12-01
coleção:	Materials Today Bio
Assuntos:	Epilepsy Icariin CD47 Nanoliposome Drug delivery
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2590006425010993
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