Multi-omics Analysis of the Role of PHGDH in Colon Cancer
Objectives : Serine metabolism is essential for tumor cells. Endogenous serine arises from de novo synthesis pathways. As the rate-limiting enzyme of this pathway, PHGDH is highly expressed in a variety of tumors including colon cancer. Therefore, targeted inhibition of PHGDH is an important strateg...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
SAGE Publishing
2023-01-01
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| Serier: | Technology in Cancer Research & Treatment |
| Online adgang: | https://doi.org/10.1177/15330338221145994 |
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