Single cell transcriptomics of human psoriasis and epidermal specific Ube2l3 deficient mice highlight CXCL16/CXCR6 involvement in psoriasis development

Abstract Psoriasis is a chronic, complex immune-mediated inflammatory disorder with cutaneous and systemic manifestations in which keratinocytes, dendritic cells and T cells have central roles. UBE2L3 may be a protective biomarker that regulates the pathogenesis of psoriasis. Here, we identify the I...

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Autores principales:	Xue-Yan Chen, Li-Ran Ye, Ni-Chang Fu, Si-Qi Chen, Bing-Xi Yan, Yu-Xin Zheng, Xi-Bei Chen, Yuan Zhou, Ming-Yue Lv, Ying-Zhe Cui, Fan Xu, Min Zheng, Xiao-Yong Man
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2025-10-01
Colección:	Nature Communications
Acceso en línea:	https://doi.org/10.1038/s41467-025-64106-6
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