Heterogeneity in response to neoadjuvant therapy in HER2-positive breast cancer — impact of HER2 score, hormonal receptor status, and Ki-67 proliferation index

INTRODUCTION: Human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC) is a biologically heterogeneous disease, exhibiting varying responses to neoadjuvant therapy. This study aimed to assess the predictive value of the HER2 immunohistochemical (IHC) score, hormone receptor (HR) s...

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Auteurs principaux:	Heba M. Sami, Mervat M. El Deftar, Marwa N. Abd Al-Hafez, Marwa M. Selim, Heba M. El-Zawahry
Format:	Artigo
Langue:	Inglês
Publié:	Via Medica 2026-10-01
Collection:	Oncology in Clinical Practice
Sujets:	HER2-positive breast cancer Ki-67 HER2 score ER PR pathological complete response neoadjuvant therapy
Accès en ligne:	https://journals.viamedica.pl/oncology_in_clinical_practice/article/view/107133
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