Chronic Lymphocytic Leukemia (CLL): evaluation of AKT protein kinase and microRNA gene expression related to disease pathogenesis

Abstract The present study evaluated 56 patients diagnosed with Chronic Lymphocytic Leukemia (CLL) and a control group of 44 clinically healthy subjects with no previous history of leukemia. Genetic expressions of AKT and microRNAs were evaluated by quantitative PCR (qPCR). A significant increase in...

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Hlavní autoři:	Lorena Caixeta Gomes, Rodrigo Ribeiro Resende, Ricardo Cambraia Parreira, Cláudia Natália Ferreira, Edna Afonso Reis, Rita Carolina Figueiredo Duarte, Luan Carlos Vieira Alves, Sergio Schusterschitz da Silva Araújo, Maria das Graças Carvalho, Adriano de Paula Sabino
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Universidade de São Paulo, Faculdade de Ciências Farmacêuticas 2022-07-01
Edice:	Brazilian Journal of Pharmaceutical Sciences
Témata:	Chronic Lymphocytic Leukemia AKT protein kinase microRNAs Apoptosis
On-line přístup:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100649&tlng=en
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