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Multiple phenotype association tests based on sliced inverse regression

Abstract Background Joint analysis of multiple phenotypes in studies of biological systems such as Genome-Wide Association Studies is critical to revealing the functional interactions between various traits and genetic variants, but growth of data in dimensionality has become a very challenging prob...

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Hauptverfasser: Wenyuan Sun, Kyongson Jon, Wensheng Zhu, the Alzheimer’s Disease Neuroimaging Initiative
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2024-04-01
Schriftenreihe:BMC Bioinformatics
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Online-Zugang:https://doi.org/10.1186/s12859-024-05731-8
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