Epigallocatechin gallate triggers apoptosis by suppressing de novo lipogenesis in colorectal carcinoma cells

The de novo lipogenesis (DNL) pathway has been identified as a regulator of cancer progression and aggressiveness. Downregulation of key lipogenesis enzymes has been shown to activate apoptosis in cancerous cells. Epigallocatechin gallate (EGCG) inhibits cancer cell proliferation without causing cyt...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Phuriwat Khiewkamrop, Damratsamon Surangkul, Metawee Srikummool, Lysiane Richert, Dumrongsak Pekthong, Supawadee Parhira, Julintorn Somran, Piyarat Srisawang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2022-05-01
coleção:	FEBS Open Bio
Assuntos:	apoptosis colorectal cancer de novo lipogenesis epigallocatechin gallate PI3K/Akt/mTOR/SREBP‐1c signaling
Acesso em linha:	https://doi.org/10.1002/2211-5463.13391
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!