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A silent sulfonamide-resistant microbial world: The curious case of missing DHPS in candidate phyla radiation

Candidate phyla radiation (CPR) microbes exhibit minimal genomes, episymbiotic/parasitic lifestyles, and metabolic dependencies on host cells. In this study, we look for the presence of dihydropteroate synthase (DHPS) and dihydrofolate reductase, key folate biosynthesis enzymes targeted by sulfonami...

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Auteurs principaux: Riyad Razzouk, Adel Azour, Jean-Marc Rolain, Fadi Bittar
Format: Artigo
Langue:Inglês
Publié: Elsevier 2025-09-01
Collection:Journal of Global Antimicrobial Resistance
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Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2213716525001602
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