Autophagy and inflammasome activation are associated with poor response to FLT3 inhibitors in patients with FLT3-ITD acute myeloid leukemia

Abstract Beyond its clinical diversity and severity, acute myeloid leukemia (AML) is known for its complex molecular background and for rewiring biological processes to aid disease onset and maintenance. FLT3 mutations are among the most recurring molecular entities that cooperatively drive AML, and...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Brunno Gilberto Santos de Macedo, Manuela Albuquerque de Melo, Diego Antonio Pereira-Martins, João Agostinho Machado-Neto, Fabíola Traina
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2024-10-01
Цуврал:	Scientific Reports
Нөхцлүүд:	Acute myeloid leukemia Autophagy Inflammasome FLT3-ITD inhibitors Drug resistance
Онлайн хандалт:	https://doi.org/10.1038/s41598-024-74168-z
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!