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Diffuse Large B-Cell Lymphoma: From Molecular Stratification to Precision Immunotherapy

Diffuse large B-cell lymphoma (DLBCL) is a biologically heterogeneous mature B-cell neoplasm whose classification, prognosis, and therapy have been reshaped by advances in genomic, transcriptomic, epigenomic, single-cell, and spatial profiling technologies. This review focuses on how these approache...

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Main Authors: Akbar Pasha, Aayushi Velingkar, Ramita Sharma, Priyanka Tiwari, Manasi Mundada, Rohan Tewani, Dylan T. Jochum, Rashid Mir, Faiq Ahmed, Sugunakar Vuree, Gopal Gopisetty, Senthil J. Rajappa, Aisha Ahmad Al-Khinji, Mallick Saumyaranjan, Chengfeng Bi, Waseem G. Lone
Format: Artigo
Language:Inglês
Published: MDPI AG 2026-06-01
Series:Cells
Subjects:
diffuse large B-cell lymphoma
cell-of-origin classification
genomic profiling
tumor microenvironment
personalized therapy
circulating tumor DNA
Online Access:https://www.mdpi.com/2073-4409/15/13/1188
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